Insulomin-R 60 tablets YAMAMOTO

What is Insulomin-R® and what is it used for?

Yamamoto® Nutrition Insulomin-R is a food supplement developed to support the carbohydrate metabolism , improve insulin sensitivity and maintain stable blood glucose levels . Entirely based on plant extracts (berberis, bitter melon, gymnema, cinnamon) and added chromium and R-alpha-lipoic acid, Insulomin-R is a GDA ( Glucose Disposal Agent ) innovative, complete and effective, able to help the body to absorb carbohydrates more efficiently and direct them towards the formation of muscle and liver glycogen.

It is known that diets characterized by an excess of carbohydrates over a long period of time can contribute to decreased insulin sensitivity , resulting in systemic inflammation and tendency to accumulate body fat .

Persistently elevated insulin levels ( hyperinsulinemia ) can cause alterations in the body's ability to utilize carbohydrates and even in their metabolism by muscle cells, resulting in excess unused circulating glucose, which will be converted into triglycerides through a process known as " de-novo lipogenesis ." The triglycerides produced will then be deposited in adipose tissue, fueling an altered metabolic state that is clearly counter to both athletic and general health goals.

In fact, all athletes need to maintain a correct nutrients partitioning , that is, a efficient distribution of macronutrients : ensuring good insulin sensitivity, thanks to training, nutrition and supplementation is essential to improve the management of carbohydrates by muscle cells, promoting their use for the production of glycogen and consequently optimising both the performance that the recovery .

The role of GDA is, in fact, to ensure that the insulin released by the pancreas following the ingestion of a carbohydrate-rich meal can direct the carbohydrates towards the muscle cells, making the muscle-building phase more effective. Using a GDA supplement does not exclude first of all adjusting the diet, which must be varied and balanced, but Insulomin-R can help in the following: Supports metabolic health by resensitizing cells to insulin action, significantly restoring proper carbohydrate absorption. This action is clearly beneficial not only for athletes and sportspeople, but also in cases of insulin resistance.

What elements does Insulomin-R® consist of?

The elements that give Insulomin-R its strength of action are Lipoic acid , Berberis extract ( Berberine ), bitter melon (Momordicin®), the extract of Gymnema Sylvestre , the cinnamon and the Chromium Picolinate . This synergy of active ingredients enhances the natural action of insulin, promoting a greater flow of glucose to muscle cells, reducing the possibility of this sugar being converted and stored in adipose tissue.

Lipoic Acid It is a fat-soluble molecule abundantly present in mitochondria, and its use is recommended for the treatment of hyperglycemia. and also for the female population who suffer from polycystic ovary syndrome (PCOS). It is proposed as a non-pharmacological solution for pre-diabetes to normalize blood sugar levels, and has numerous scientific studies supporting its effectiveness, clearly demonstrating the benefits derived from its use.

There Berberine , obtained from the extract of berberis, is a powerful alkaloid recommended for those suffering from insulin resistance and for glycemic management . Its action is expressed by activating AMPK ( Adenosine Monophosphate activated Protein Kinase ), a key enzyme for cellular energy metabolism. The activation of AMPK has the main effects of stimulation of hepatic fatty acid oxidation , the ketogenesis , the slowing down of lipogenesi (fat formation) and inhibition of cholesterol and triglyceride synthesis. This enzyme also stimulates glucose uptake by the muscles and modulates insulin secretion by pancreatic beta cells. Using berberine therefore allows for improved carbohydrate utilization by muscle cells, supporting glycogen synthesis and recovery.

The bitter melon (also called bitter melon or Mormodica Charantia ) appears to have a powerful insulin-sensitizing effect , therefore useful for improving problems of insulin resistance (caused by high sugar consumption for a long time, bulking phases or prolonged hyperglycemia). Modern scientific evidence agrees in confirming bitter melon as one of the most promising plants for the natural treatment of diabetes : it can in fact stimulate insulin secretion (through complex mechanisms of action that include the activation of AMPK and the inhibition of PTP1B, which usually deactivates the insulin receptor), and increase the expression of the membrane glucose transporter GLUT-4.

Also the extract of the climbing plant Gymnema Sylvestre It is interesting for its contribution to weight control: its leaves are rich in polyphenols and triterpene glycosides (such as gurmarina and gymnemic acid A1 ), substances that act by binding to the taste receptors on the tongue (gurmarin), mitigating the perception of the sweet taste and Consequently, it reduces the craving for sugary foods , as well as the glucose present in the intestinal tract (gymnemic acid A1), reducing the absorption of sugars. On average, the blockage of glucose receptors occurs within an hour of taking gymnema and lasts for several hours: scientific literature even seems to suggest a parallel regeneration of the endocrine cells of the pancreas. As a result, the body's cells, on the one hand, will absorb less glucose and, on the other, will be able to easily convert the ingested sugars into fuel for the body.

There Cinnamon It is well known not only as a spice but also for its ability to Maintain low blood sugar levels : It can inhibit several pancreatic enzymes that digest starch, malt, and sucrose (such as alpha-amylase, maltase, and intestinal sucrase). This prevents the sugars and starches introduced with meals from being digested, slowing the absorption of glucose into the blood.

The chrome It contributes to the maintenance of normal blood glucose levels and normal macronutrient metabolism; its picolinate form is more easily absorbed than other forms, supporting the objective of Insulomin-R: improve the vehicle And the use of carbohydrates that we ingest , both in phases of building muscle tissue that of weight loss .

• AR = Reference assumptions