Coletix 30 tablets YAMAMOTO

From the constant research of the Yamamoto® Research R&D team comes Coletix, a food supplement based on Olecol® certified olive extract , red yeast rice ( Monascus purpureus ), gamma oryzanol and completed with coenzyme Q10 , which thanks to the synergy of the active ingredients contained supports a good blood circulation and the regularity of the blood pressure . Coletix provides 58 mg/daily dose of fermented red rice titrated at 2.76% in total monacolins ( 2.76 mg per daily dose, in compliance with the new European regulations on the use of Monacolin K ).

Cardiovascular diseases are currently among the leading causes of disability and mortality in Western and developing countries, and are favored by unhealthy lifestyles, unbalanced diets, excessive consumption of junk food, little or no physical activity, and smoking. The main factors that influence the susceptibility to cardiovascular diseases and disorders are cholesterol imbalance (hypercholesterolemia), hypertriglyceridemia, hypertension, diabetes, and insulin resistance, as well as obesity. Specifically, it is important to: keep the entire lipid balance under control in order to protect themselves from the formation of atherosclerotic plaques along the walls of blood vessels, favored by inflammation and hypertension, which will potentially risk obstructing the vessels and causing very serious consequences on the cardiovascular system.

Coletix is the product that Yamamoto® Research has developed for promote and support good blood circulation , heart health and maintain Normal blood triglyceride levels . A titrated and standardized plant extract was chosen for the formulation, which allows the natural active ingredients to be kept qualitatively and quantitatively constant, ensuring product stability, bioavailability, and efficacy. The product presents the following synergies:

• Olecol® Olive Extract ;

• Red yeast rice ;

• Gamma oryzanol ;

• Coenzyme Q10 .

In detail, the Monacolin K from red yeast rice It is a molecule belonging to the Monacolin group, which originates from the fermentation of the common red cooking rice Oryza sativa thanks to the action of yeast Monascus purpureus , also known as " red yeast ", which gives it its characteristic color. Always used in oriental cuisine as a substitute for vinegar and as a health agent, the fermentation of this rice allows us to obtain numerous substances, monacolins, which have a hypocholesterolemic action . In fact, Traditional Chinese Medicine suggests the consumption of fermented red rice for treat circulatory disorders and also in cases of gastrointestinal problems, but the discovery of the molecule to which many of the beneficial characteristics are attributed dates back to 1979. In that year, Professor Aika Endo, studying the fermentation of "red yeast", discovered that a metabolite produced in the fermentation process could inhibit the enzyme HMG-CoA-reductase, one of the main enzymes involved in the synthesis of cholesterol (which occurs in the liver): this metabolite was precisely Monacolin K.

Herbal statins, such as Monacolin K, have been shown to possess cholesterol-lowering properties . Consumption must, however, adhere to the recommended doses in compliance with current regulations to avoid side effects such as weakness, muscle pain, gastrointestinal or liver problems.

Olive extract favors the normal blood circulation and the Regular blood pressure . The Oleuropein contained in Coletix is represented by Olecol®, a patented Bioactor product, highly water-soluble, standardized, extracted from olive leaves, with a very high concentration of bioavailable Oleuropin, which has been shown to promote normal blood circulation and regular blood pressure thanks to a dual mechanism of action. It is a natural ingredient that offers a safe approach to managing blood lipid levels, capable of combating lipid oxidation and whose effectiveness has also been demonstrated by multiple randomized, placebo-controlled studies.

The gamma oryzanol It is a substance extracted from rice bran oil; it is also present in wheat bran, some fruits, and certain vegetables.

The Coenzyme Q10 , also known as ubiquinone due to its ubiquitous role in the body, is a very important molecule for our body. It is mainly present in the mitochondria, the energy centers of cells, and also in the heart muscle, although it is present in many human tissues. It is involved in the electron transfer processes of the cell, and is a powerful antioxidant which protects membranes from oxidative damage. Since cholesterol-lowering statins also reduce the production of Coenzyme Q10, it is very useful to replenish this substance when taking active ingredients, even natural ones, that could lower physiological levels.